Empress Recode (Exosomes)
Exosomes are extracellular vesicles that carry growth factors, peptides, and signaling molecules between cells. In aesthetic medicine they are used to support the skin's own repair processes: they signal fibroblasts to increase collagen and elastin production, help regulate inflammation, and support barrier recovery. At The Empress LA, exosomes are applied immediately following microneedling, which creates controlled microchannels that allow the formulation to reach the dermal layer where it is most effective. This treatment is commonly used for fine lines, uneven tone and texture, acne scarring, and dull or compromised skin. Results develop over several weeks as new collagen forms, and a series of treatments is generally recommended.
HOW IT WORKS
Microneedling creates controlled microchannels through the epidermis into the upper dermis. Exosomes — extracellular vesicles isolated from stem cells — are then applied to the treated surface, where those channels allow their growth factors, peptides, and anti-inflammatory signaling molecules to reach the dermis.
Once absorbed, exosomes signal fibroblasts to increase collagen and elastin production, support cellular repair, and help regulate inflammation. Improvement in tone, texture, and firmness develops gradually over the following weeks as new collagen forms, rather than appearing immediately after treatment.
WHAT TO EXPECT
Your appointment begins with a cleanse and a topical anesthetic, left in place for approximately 20–30 minutes. Microneedling is then performed at a depth selected for the treatment area, followed by application of the exosome serum to the freshly created microchannels.
Total appointment time is 60–75 minutes. Most patients describe the treatment as tolerable, with a light prickling sensation. Expect redness and a flushed appearance for 24–48 hours, and possible tightness or dryness for 1–3 days. Visible improvement in texture and tone typically begins around days 5–7 and continues to build.
FAQs
How much treatment will I need?
A series of 3 to 4 sessions spaced 4 to 6 weeks apart is recommended for most patients. Collagen remodeling is cumulative, so each session builds on the last. Maintenance sessions every 3 to 6 months help sustain results. Your specific series is determined at consultation based on your skin type, concerns, and treatment history.
Does it hurt?
A topical numbing cream is applied before the treatment begins. During microneedling, most patients feel a light vibration or pressure. The treatment is generally well tolerated and is rarely described as painful.
What's the Downtime?
Downtime is minimal. After treatment you may have a pink flush, mild tightness, or dryness, which usually resolves within 24 to 72 hours. Light flaking or mild sensitivity may occur between days 2 and 5 as the skin turns over. There is no harsh peeling. Avoid makeup, heat, and sun exposure for the first 48 hours, and keep the skin hydrated with gentle products.
How long do results last?
After a completed series of 3 to 4 sessions, most patients see improvement lasting 6 to 12 months. Because exosomes work by stimulating your own collagen and elastin production, results develop over several weeks rather than appearing immediately. Daily SPF, a consistent skincare routine, and periodic maintenance sessions extend the duration of results.
Are there any side effects?
Side effects are typically mild and short-lived. Expect redness and warmth for 24 to 72 hours, and mild tightness or dryness as the skin heals. Light flaking or shedding may occur between days 2 and 5. Pinpoint bruising and minor swelling are possible from the microneedling itself and usually resolve within a few days. Because exosomes are anti-inflammatory and biologically compatible, adverse reactions are uncommon.
Every treatment begins with a consultation and medical history review to confirm you are an appropriate candidate.
What do I need to do before my appointment?
Stop retinoids, acids, and physical exfoliants 5 to 7 days before your appointment. Reschedule if you have sunburn, an active breakout, or a cold sore in the treatment area, or if you have had a laser treatment in that area recently.
For 48 to 72 hours prior, avoid blood-thinning supplements such as fish oil, ginkgo, and high-dose vitamin E unless prescribed, and limit alcohol to reduce bruising risk. Arrive with clean, makeup-free skin and avoid sun exposure and tanning. Hydrate well the day before.
What do I need to know post treatment?
For the first 24 to 48 hours, avoid makeup, sweating and exercise, sun exposure, and touching the treated area. Warmth, tightness, and mild flushing are expected as the skin heals. Do not use exfoliants, retinoids, or active skincare until cleared by your provider; use gentle cleansing, a bland moisturizer, and daily SPF instead.
Flaking or dryness between days 2 and 5 is normal. Drink plenty of water and rest. Results continue to develop over the next 1 to 4 weeks as new collagen forms. Contact the office if you develop increasing pain, spreading redness, blistering, or drainage.
Disclaimer: This information provided is for general informational purposes only. It is not intended as a substitute for professional advice from a qualified healthcare professional and should not be relied upon as personal health advice. The information contained in this content is not meant to diagnose, treat, cure, or prevent any disease. You are advised to consult with a qualified healthcare professional for any medical concerns. Use of this information is at your own risk. We are not responsible for any adverse effects, or consequences resulting from the use of any suggestions or information provided.

